Study Background
♦Fibrosis, as assessed by liver biopsy, is the primary determinant of disease progression in patients with nonalcoholic steatohepatitis (NASH)♦ Liver biopsy plays an integral role in the diagnosis and monitoring of disease progression, both in routine clinical practice and clinical trials
♦ Human pathologist staging of fibrosis is limited by intra- and inter-reader variability
♦ Machine learning (ML) approaches to interpretation of liver histology may enable more reliable and quantitative assessment of both traditional and novel histologic features, with potential prognostic relevance in NASH Taylor-Weiner et al
