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Characteristics of the tumor microenvironment in IDH1-mutated cholangiocarcinoma patients from ClarIDHy trial

Using machine learning models to quantify histologic features of the CCA pre-treatment tissue sections, we aimed to identify correlates of tumor microenvironment associated with:
  • IDH1 mutation status
  • Early disease progression (patients experienced progression or death within 1.54 months)
  • Plasma 2-HG levels (median, 630 ng/ml)
Saatcioglu et al.
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