Tissue and cell classification
Automated detection and AI heatmaps visualizing >20 tissue regions and >10 cell types
H&E fibrosis detection & subtyping
AI-powered identification of collagen/fibrosis tissue - directly on H&E image without additional slide scanning
HIF Panel
>1,000 curated HIFs for rapid, scalable, and standardized quantification of the entire tissue
Fibrosis Subtyping
- Portal fibrosis
- Periportal fibrosis
- Perivenular fibrosis
- Perisinusoidal fibrosis
- Incomplete septal fibrosis
- Complete septal fibrosis
- Nodular fibrosis
Landmarks
- Portal tract
- Central vein
- Zone 1
- Zone 2
- Zone 3
Cell Type & Tissue Region Classification
- Immune cells
- Normal hepatocytes
- Ballooned hepatocytes
- Steatotic hepatocytes
- Bile ducts
- Blood vessels
- Portal inflammation
- Interface hepatitis
- Lobular inflammation
Product Profile
- Indications: Metabolic dysfunction-associated steatohepatitis
- Intended Use: Research Use Only
- Stain Type: H&E
- Scanners: Leica Aperio® AT2
- Outputs: Panel (.csv) for >1,000 quantitative Human Interpretable Features (HIFs); Heatmap classification of tissue, cells, fibrosis subtypes and liver landmarks.
Liver Explore1 may be compatible with other liver indications and scanners. Please contact us for more information.
Unlocking novel insights for the future of MASH drug development
Improve
Quantification of established histologic biomarkers of MASH (e.g., patterns of fibrosis, counts of ballooned hepatocytes)
Identify
Novel histological biomarkers and drivers of therapeutic efficacy
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Generate
Comprehensive supporting evidence for regulatory submission
