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AIM-TumorCellularity (AIM-TC)

Automated, whole-slide level assessment of tumor cellularity, or tumor fraction

AIM-TC - Tumor Cellularity Quantification

AIM-TC1 is PathAI’s pan-tumor product that quantifies the areas of tumor and tissue, and supports tumor cellularity assessments required for successful NGS. AISight®, PathAI’s digital pathology image management system, enables access to a menu of algorithm products that can be utilized to increase efficiency and turnaround time of routine laboratory tasks.

Increase success rate of NGS

Run on a standard H&E whole slide image, AIM-TC can automatically determine the tumor area and percentage of tumor nuclei.

Streamline Review

Tumor cellularity assessment can be time consuming, particularly when tumor content is low. AIM-TC may reduce the amount of pathologist time spent on tumor cellularity assessments.

Automate Assessment

AIM-TC provides standardized, quantitative metrics to support more accurate determination of tissue inputs.

Product Profile

Scanners: Leica GT450, Leica AT2, Hamamatsu S360, Roche DP200 and DP600, Philips UFS

Specimen Type: Biopsy, Resection

Tumor Type: Trained as a pan-carcinoma product with training and verification data on 14+ tumor types including NSCLC, breast, CRC, melanoma, gastric, RCC, PDAC, prostate, DLBCL, ovarian, bladder, HNSCC, HCC, and SCLC.

Stain Types: H&E

Primary Outputs

Key Result:

  • Total area of tissue (mm2)

  • Total area of tumor (mm2)

  • Percent tumor nuclei (%)

Supporting Results:

  • Area of cancer (mm2)

  • Area of stroma (mm2)

  • Area of necrosis (mm2)

  • Number of cancer cells

  • Total number of cells in tissue

Training data

2M+ expert pathologists annotations from 500+ Board-Certified Pathologists​

 

"AIM-TC is a great example of how AI can augment the pathology laboratory and eliminate routine, stressful and time-consuming activities, allowing pathologists to focus on what they do best. We expect that if implemented widely in our practice, AIM-TC can save hundreds of hours of pathologist time that can instead be used for case sign-off and patient care."

- Tobias Kull, PhD., bioinformatician in the Molecular Pathology Unit of University Hospital Zurich

AI-Powered Tumor Sufficiency Assessment Product Available on AISight

Pathologist-Centric Visualization & Quantification

The model is designed around the pathologist’s workflow, with optional H&E overlays that stay off by default and can be enabled on demand to clearly highlight tumor regions and support single-cell–level tumor cell quantification as the user zooms in.

Tumor Sufficiency Outputs in the Side Panel

Provides key tumor sufficiency outputs for molecular testing in a convenient side panel for quick review.

Annotation Insights

Allows users to draw regions of interest and view supported AI results in real time to enable faster area-specific quantification and reduce repetitive counting.

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Contact Us

Connect with our business development team to learn more about AIM-TumorCellularity.

¹AIM-TumorCellularity is for Research Use Only. Not for use in diagnostic procedures in the US. AISight® is for research use only. Not for use in diagnostic procedures.