Skip to content

AIM-HER2 Breast Cancer

AI-based Measurement of HER2 Scoring

AIM-HER2 delivers automated and reproducible digital HER2 scoring with explainable AI heatmap visualizations. Now available on the AISight™ Image Management System.1

Specifications

  • Intended Use: Research Use Only
  • Indications: Breast Cancer
  • Clones: Ventana 4B5 and Dako HercepTest
  • Scanners: Leica Aperio® AT2 and GT450; Hamamatsu NanoZoomer® s360
  • Inputs: Breast cancer biopsy, resection, and/or excision sample from primary, recurrent, or metastatic tumor (excluding in situ tumor)
  • Outputs: HER2 score (0, 1+, 2+, 3+); Area of invasive carcinoma; Additive multiple instance learning (aMIL) density heatmap

AIM-HER2 Breast Cancer may be compatible with additional scanner types. Please contact us for more information.

AIM-HER2 Scoring Heatmaps

Additive MIL based heatmaps2 highlight tissue patterns features that most contribute to AIM-HER2's score prediction. Pathologists are able to more confidently assess HER2 expression, especially in borderline cases with more slide-level heterogeneity as they can quickly and more easily focus on the most critical features and slide areas.

“I like that these heatmaps correlate to the likelihood that the region is a particular score. It gives me the immediate intuition as to the parts of the slide I should focus on.”

— Health System Pathologist, UK Cancer Center

Rigorously trained and tested

157 K

Annotations

12 K

Slide-level HER2 scores

4 K

Slides

65 +

Board-certified breast pathologists

iStock-1263308819-1400px (2)

Contact Us

Connect with our team to learn more about AIM-HER2.

1AIM-HER2 is for Research Use Only. Not for use in diagnostic procedures.
2 Javed, et al. Additive MIL: Intrinsically Interpretable Multiple Instance Learning from Pathology. Computer Vision and Pattern Recognition, June 2022. arXiv:2206.01794