---
title: Machine Learning Based Quantification of Histology Features from Patients Treated for Chronic Hepatitis B Identifies Features Associated with Viral DNA Suppression and HBeAg Loss
description: Machine Learning Based Quantification of Histology Features from Patients Treated for Chronic Hepatitis B Identifies Features Associated with Viral DNA Suppression and HBeAg Loss
---

[PathAI Resources ](https://www.pathai.com/resources)

# [Machine Learning Based Quantification of Histology Features from Patients Treated for Chronic Hepatitis B Identifies Features Associated with Viral DNA Suppression and HBeAg Loss](https://www.pathai.com/resources/machine-learning-based-quantification-of-histology-features-from-patients-treated-for-chronic-hepatitis-b-identifies-features-associated-with-viral-dna-suppre)

 Written by [Admin](https://www.pathai.com/resources/author/admin) | Nov 13, 2020 5:00:00 AM

## Study Background

 ♦Chronic hepatitis B virus (CHB) infection is associated with cirrhosis, liver decompensation, and hepatocellular carcinoma

♦ HBV DNA suppression and hepatitis B e antigen (HBeAg) loss are important outcomes for patients undergoing treatment for CHB infection; however, the relationships of these outcomes with histology have not been fully elucidated

♦ Computational pathology leveraging convolutional neural networks could facilitate characterization of histologic features associated with HBV DNA suppression and HBeAg loss Shukla et al.

[View Poster](https://www.pathai.com/hubfs/2025%20Assets/Copy-of-Shukla-AASLD-2020-68x44@100-Final.pdf)

[View full post](https://www.pathai.com/resources/machine-learning-based-quantification-of-histology-features-from-patients-treated-for-chronic-hepatitis-b-identifies-features-associated-with-viral-dna-suppre)

```json
{
  "@context" : "http://schema.org",
  "@type" : "BlogPosting",
  "author" : {
    "@type" : "Person",
    "name" : "Admin"
  },
  "dateModified" : "2025-08-06T20:59:39.840Z",
  "datePublished" : "2020-11-13T05:00:00Z",
  "headline" : "Machine Learning Based Quantification of Histology Features from Patients Treated for Chronic Hepatitis B Identifies Features Associated with Viral DNA Suppression and HBeAg Loss",
  "image" : {
    "@type" : "ImageObject",
    "height" : 60,
    "url" : "/hs/hsstatic/content_shared_assets/static-1.4092/img/default-amp-logo.png",
    "width" : 60
  },
  "mainEntityOfPage" : "https://www.pathai.com/resources/machine-learning-based-quantification-of-histology-features-from-patients-treated-for-chronic-hepatitis-b-identifies-features-associated-with-viral-dna-suppre",
  "publisher" : {
    "@type" : "Organization",
    "logo" : {
      "@type" : "ImageObject",
      "height" : 60,
      "url" : "/hs/hsstatic/content_shared_assets/static-1.4092/img/default-amp-logo.png",
      "width" : 60
    },
    "name" : "PathAI Resources"
  }
}
```