Usual interstitial pneumonia (UIP) is characterized by heterogeneous histologic patterns, including honeycomb changes, foci of fibroblasts, and paraseptal and subpleural fibrosis [1].
Despite progress in understanding the extracellular matrix composition in UIP, quantitative characterization of these histologic patterns is still limited.
Quantitative multimodal anisotropy imaging (QMAI) allows the visualization of individual collagen fibers in hematoxylin and eosin (H&E)-stained tissue samples.
Our study aim was to utilize QMAI to compare fibrosis features between UIP and normal lung tissue.
Conference
Pathology Visions 2024
Partner
Eli Lily, Wake Forest
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