---
title: "AI-based estimation of tumor cell percentage in NSCLC, CRC and breast cancer: agreement analysis and feature overview from digital pathology algorithms"
description: "AI-based estimation of tumor cell percentage in NSCLC, CRC and breast cancer: agreement analysis and feature overview from digital pathology algorithms"
---

[PathAI Publications ](https://www.pathai.com/publications)

# [AI-based estimation of tumor cell percentage in NSCLC, CRC and breast cancer: agreement analysis and feature overview from digital pathology algorithms](https://www.pathai.com/publications/ai-based-estimation-of-tumor-cell-percentage-in-nsclc-crc-and-breast-cancer-agreement-analysis-and-feature-overview-from-digital-pathology-algorithms)

 Written by [Admin](https://www.pathai.com/publications/author/admin) | Sep 6, 2025 4:00:00 AM

## Background & Objectives

Estimation of tumor cell percentage (TC%) is a mandatory pre-analytical step before molecular testing in non-small cell lung cancer (NSCLC) yet remains poorly reproducible and imprecise when performed manually by pathologists. While tumor recognition relies on pathologist expertise, TC% quantification is a mathematical task for which the human eye is poorly suited.

## Conference

European Congress of Pathology 2025

[View Poster](https://drive.google.com/file/d/1B32HjExMzua5_mL5j9lAVUBg7K2IQRo9/view)

[View full post](https://www.pathai.com/publications/ai-based-estimation-of-tumor-cell-percentage-in-nsclc-crc-and-breast-cancer-agreement-analysis-and-feature-overview-from-digital-pathology-algorithms)

```json
{
  "@context" : "http://schema.org",
  "@type" : "BlogPosting",
  "author" : {
    "@type" : "Person",
    "name" : "Admin"
  },
  "dateModified" : "2026-01-09T20:26:20.048Z",
  "datePublished" : "2025-09-06T04:00:00Z",
  "headline" : "AI-based estimation of tumor cell percentage in NSCLC, CRC and breast cancer: agreement analysis and feature overview from digital pathology algorithms",
  "image" : {
    "@type" : "ImageObject",
    "height" : 60,
    "url" : "/hs/hsstatic/content_shared_assets/static-1.4092/img/default-amp-logo.png",
    "width" : 60
  },
  "mainEntityOfPage" : "https://www.pathai.com/publications/ai-based-estimation-of-tumor-cell-percentage-in-nsclc-crc-and-breast-cancer-agreement-analysis-and-feature-overview-from-digital-pathology-algorithms",
  "publisher" : {
    "@type" : "Organization",
    "logo" : {
      "@type" : "ImageObject",
      "height" : 60,
      "url" : "/hs/hsstatic/content_shared_assets/static-1.4092/img/default-amp-logo.png",
      "width" : 60
    },
    "name" : "PathAI Publications"
  }
}
```