Introducing PathExplore™ IOP
Empowering cancer drug developers and clinical researchers with AI-powered insights.1
PathExplore™ IOP: Immuno-Oncology Profiling
PathExplore™ IOP (Immuno-Oncology Profiling) offers unparalleled visual and quantitative characterization of patterns of lymphocyte infiltration within the tumor and stroma. This innovation allows classification of immune phenotype based on diagnostic H&E images, facilitating deeper insights into immune response characteristics.
Enhance Immune-Oncology Profiling workflows with spatial characterization of tumor-infiltrating lymphocytes (TILs) in the tumor microenvironment (TME) directly from H&E.
Identify, quantify, and classify TILs and immune phenotypes with high spatial resolution
- Visualize the density and spatial distribution of TILs with single-cell resolution
- Identify High and Low TIL density regions within tissue regions
- Analyze TIL populations and distributions by tissue compartments
- Quantify cell-cell interactions between tumor and immune cells
- Curated features designed to characterize the tumor-immune microenvironment
Distinct immune profiles (IP) stratifies patient prognosis and treatment response
- Measure % of “High TIL” and “Low TIL” micro patches in each tissue area enables accurate classification of immune phenotypes taking into account heterogeneity of distribution
- Quantitative analytics is used to identify generalizable thresholds for assigning slide-level-based IPs
- Investigations indicate promising applications of IP for patient stratification and novel biomarker discovery
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1 PathExplore™ IOP is for research use only. Not for use in diagnostic procedures.