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Immunohistochemistry (IHC) · Oncology
The specificity is directed against surface as well as hidden determinants and has been ascertained by gel precipitation techniques and immunohistochemistry. The antibody labels plasma cells and related lymphoid cells containing lambda light chains, and it is a useful tool for the classification of patients with monoclonal gammopathies and amyloidosis. Additionally, the antibody may be used for distinguishing neoplastic monoclonal proliferation from reactive hyperplasia of B cells.