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Immunohistochemistry (IHC) · All
The Ki-67 antigen is a large nuclear protein (345, 395 kDa) preferentially expressed during all active phases of the cell cycle (G1, S, G2 and M-phases), but absent in resting cells (G0-phase). In diagnostic histopathology and cell biology, antibodies against the Ki-67 antigen have proven valuable by allowing direct monitoring of the growth fraction of normal and neoplastic cells.