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Immunohistochemistry (IHC) · All
It labels mesothelioma, and epithelial basal cells in prostate and tonsil. No reactivity with other mesodermally derived tissues, such as muscle and connective tissues, has been observed. Cytokeratin 5/6 is expressed at low levels in adenocarcinomas, whereas it is present at high levels in epithelioid mesotheliomas, and the antibody is, therefore, very useful in the differentiation between these types of cancer.