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Immunohistochemistry (IHC) · Oncology
The antibody is a pan-T cell marker for detection of normal and neoplastic T cells. It is well-suited for detecting reactive T cells in tissue with lymphoid infiltrates, and for diagnosing T-cell neoplasms. The antibody cross-reacts with T cells in many animal species (1). In conjunction with Dako Monoclonal Mouse Anti-Human CD20cy (Code M0755), the antibody is well-suited for the differentiation between T and B cells in formalin-fixed tissue (2). Futhermore, antibodies against CD3 may aid in the differential diagnosis of Hodgkin's disease where CD3 is rarely expressed (3).